Efeito agudo de uma sessão de exercícios com pesos associados à suplementação de glutamina sobre as funções cognitivas de pessoas com HIV/AIDS

Abstract

This study aimed to investigate the effect of an exercise session with weights associated with glutamine supplementation on cognitive function of people with HIV/ AIDS. The sample consisted of 10 HIV+ women, who used the Antiretroviral Therapy Highly Active (45.00 i 12.77 years; 65.71 i 12.04 kg, 1.54 i 0.05 cm). The participants were randomized in a double-blind procedure to receive seven days of supplementation Glutamine dipeptide (GLD) and/or placebo (PLA). At the end of this first period, the participants held a workout with weights with cognitive assessments before and immediately after the session. Then the participants rested for seven days for the initial stocks could return to baseline levels (washout). Following was the crossing of the groups, so that those who had received the GLD in the first week spent extra for seven days with PLA and vice versa, to then repeat evaluations and exercise session. In cognitive assessments used the Stroop test, which aims to assess selective attention and inhibitory control over the color of conflict and word, and the N-back test, responsible for evaluating the central executive component of working memory by stimuli visual. The exercise session consisted of seven weight exercises involving different muscle groups, with three of 8-12 repetitions with an interval of 90 seconds between sets and 120 between the years. For statistical analysis, we used the Mauchly test to check the roundness of the data, two-way ANOVA for intra and inter comparisons conditions and post hoc Bonferroni analysis for the isolated effect of factors or interaction between them. The data were processed in the Statistica software, version 7.0. The level of significance was P<0.05. The results showed the effect (P<0.01) reduction of exercise in the response time, checked by the Stroop Test. This decrease occurred in both the latency time registered by difference in time spent between the first and last reply card (pre PLA 8.6 i 7.5, post 7.7 i 5.3 PLA; pre GLD 10.2 i 6.2, 5.4 i 3.6 after GLD), and in isolation, the pre time for post-exercise (PLA card pre 15.2 i 3.6, 13.2 i 2 PLA post, 0, pre GLD 15.2 if 1.9, 14.5 if 1.8 GLD post, card B PLA pre 16.8 if 3.8, 15.6 if 3.3 PLA post; GLD pre 17.6 if 3.7; GLD after 16.5 i 2.8; C card pre PLA 23.8 i 9.4, 20.9 i 6.4 PLA post; GLD pre 25.5 i 7.5; GLD post 19, 8 i 4.9). However, there was no difference for the GLD condition, only an additional effect on the lag time from the first to the last card of the Stroop test. In the N-back, no significant results (P>0.05). It is suggested that an acute bout of exercise with weights is able to intervene positively in cognitive function, specifically in inhibitory control, people with HIV / AIDS without causing significant changes in the working memory.