Impacto da suplementação de glutamina dipeptídeo sobre os marcadores de estresse oxidativo de pessoas com HIV/AIDS submetidas a uma sessão aguda de exercícios de força

Abstract

The objective of this research was to investigate the impact of the dipeptide of glutamine supplementation on markers of oxidative stress in people with HIV/AIDS submitted to an acute bout of strength exercises. The sample consisted of 10 HIV + women (45.0 ± 12.7 years; 65.7 ± 12.0 kg, 1.5 ± 0.1 m). The study lasted for five weeks divided into three stages. In the first stage, there was familiarization with strength exercise protocol. Subsequently, rest for a week. The second stage consisted of three phases. In the first phase, the subjects were randomized; double blind, to receive seven days supplementation with glutamine dipeptide (Condition 1) and/or placebo (Condition 2). On the seventh day of supplementation, the second phase was carried out, consisting of strength training session and pre blood collection, one and two hours after the exercise session. In the third phase was the washout period. In the third stage, reversed the conditions (1 and 2). The session consisted of seven strength exercises three of 8-12 repetitions with an interval of 90 seconds between sets and 120 between the years. We used the following biomarkers of oxidative stress: TBARS, AOPP, FOX, GSH, GSSG and GSH/GSSG. Statistical Procedures for multiple comparisons were used. No significant results related to supplementation (pre), time (1 hour) and supplementation X time (2 hours). We conclude that supplementation of glutamine dipeptide no influence on markers of oxidative stress after an acute bout of strength exercise in the suggested intensity.