Infecções hospitalares causadas por Staphylococcus aureus em um hospital de ensino

Abstract

This study aimed to determine the prevalence of Staphylococcus aureus in the etiology of hospital-acquired infections in a school hospital between 2001 and 2004, highlighting the antimicrobial drug susceptibility profile. Data were retrieved from the nosocomial infection data bank and the results of exams from data bank of the automated system (MicroScan®). Seventy four oxacillin-resistant Staphylococcus aureus samples evaluated by MicroScan method, isolated in 2004, were studied using the technique of "minimal inhibitory concentration". Nosocomial infection rate was 5.8% and the infection rate for oxacillinresistant Staphylococcus aureus was 11%. The samples of Staphylococcus aureus presented a broad resistance spectrum for the evaluated antimicrobial drugs. Average prevalence of oxacillin resistance was 70.75%: vancomycin resistance was not found. The main sites of oxacillin-resistant Staphylococcus aureus infections were surgical wounds (9,,75%), blood stream (8,75%), pneumonia (6,0%), skin (3,5%) and urinary track (1,25%). The agar dilution method presented different results from those obtained by MicroScan® to detect oxacillinresistant Staphylococcus aureus samples, but no difference was found in the results for vancomycin susceptibility.